Patent · US Expired

Substituted trifluoropropan-1-yl-imidazole alpha 2-receptor anagonists

US5173502A · kind A · utility

5Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 1, 1991
Grant dateDec 22, 1992
Priority date
Expiry dateNov 1, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound selected from those of formula (I): ##STR1## in which R represents straight-chain or branched lower (C.sub.1 -C.sub.6) alkyl, (C.sub.3 -C.sub.8) cycloalkyl, optionally substituted phenyl, pyridyl or naphthyl, and PA1 R.sub.1 and R.sub.2, which are the same or different, each represents hydrogen, straight-chain or branched (C.sub.1 -C.sub.6) alkyl, or straight-chain or branched (C.sub.1 -C.sub.6) acyl, an enantiomer, diastereoisomer and epimer, and an addition salt thereof with a pharmaceutically-acceptable acid. Medicinal product, which is useful as .alpha..sub.2 -antagonist.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.