1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5175178A · kind A · utility
11Cited by
2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 4, 1990 |
| Grant date | Dec 29, 1992 |
| Priority date | — |
| Expiry date | Jun 4, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formulas ##STR1## wherein: Y is an alkylene bridge of 3-9 carbon atoms; PA0 R' is lower-alkyl or hydroxy-lower-alkyl of 1-5 carbon atoms; PA0 R.sub.1 and R.sub.2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and PA0 R.sub.8 is hydrogen or lower-alkyl of 1-5 carbon atoms, with the proviso that when R.sub.8 is hydrogen R' is hydroxy-lower-alkyl, are useful as antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.