Patent · US Expired

Lipoxygenase inhibiting compounds

US5175183A · kind A · utility

27Cited by
10References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 10, 1991
Grant dateDec 29, 1992
Priority date
Expiry dateJul 10, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/02
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Certain N-aryl, N-heteroaryl-, N-arylalkyl-, N-heteroarylalkyl-, N-arylcyclopropyl- and N-heteroaryl-cyclopropyl-N'-hydroxyurea compounds are inhibitors of lipoxygenase enzyme activity and are thus useful agents in treating disease states such as asthma, arthritis, allergy, psoriasis, inflammatory bowel disease, gout, adult respiratory distress syndrome, endotoxin shock, and other inflammatory conditions in which the products of the arachidonic acid cascade are implicated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.