Binding peptides

US5175253A · kind A · utility

Assignee

• Washington University · US

Inventors

• Robert J. Fallon · New Hudson, US
• Joseph W. Bulock · Saint Peters, US
• Steven P. Adams · Holden, US
• David Hirsch Perlmutter · Chesterfield, US

Key dates

• Filing date: Apr 24, 1991
• Grant date: Dec 29, 1992
• Expiry date: Apr 24, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/8125
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Novel short peptides of up to about 20 amino acid residues are disclosed that bind to the SEC receptor. These novel peptides preferably are pentapeptides which are synthetic analogs of a pentapeptide domain in the carboxy-terminal fragment of .alpha..sub.1 -antitrypsin (amino acids 370-374, Phe-Val-Phe-Leu-Met [SEQ ID NO:2]). A preferred binding peptide is Phe-Val-Ala-Leu-Met [SEQ ID NO;6].