Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5175320A · kind A · utility
30Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 18, 1991 |
| Grant date | Dec 29, 1992 |
| Priority date | — |
| Expiry date | Sep 18, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J51/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6.alpha.-hydroxy-7-keto-derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.