Patent · US Expired

Pharmaceutical compositions

US5177068A · kind A · utility

24Cited by
30References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 8, 1989
Grant dateJan 5, 1993
Priority date
Expiry dateMay 8, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F15/025
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Iron complexes comprising a ferric cation in combination with at least two different ligands, at least one of which is provided by a compound being: PA0 (1) 3-hydroxy-4-pyrone or a 3-hydroxy-4-pyrone in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by an aliphatic hydrocarbon group of 1 to 6 carbon atoms; or PA0 (2) a 3-hydroxypyrid-2-one or 3-hydroxypyrid-4-one in which the hydrogen atom attached to the nitrogen atom is replaced by an aliphatic acyl group, by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, or by an aliphatic hydrocarbon group substituted by one or more substituents selected from aliphatic acyl, alkoxy, alphatic amide, aliphatic ester, halogen and hydroxy groups and, optionally, in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by one of said substituents, by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, or by an aliphatic hydrocarbon group substituted by an alkoxy, aliphatic ester, halogen or hydroxy group; the charge on the ferric cation being neutralized by the charge on the ligands covalently bound thereto; are of value in medicine, particularly in the treatment of iron def…

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