Substituted pyridyl-dihydroxy-heptenoic acid and its salts

US5177080A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rolf Angerbauer · Wuppertal, DE
• Peter Fey · Wuppertal, DE
• Walter Hubsch · Wuppertal, DE
• Thomas Philipps · Cologne, DE
• Hilmar Bischoff · Wuppertal, DE
• Dieter Petzinna · Mülheim an der Ruhr, DE
• Delf Schmidt · Wuppertal, DE
• Gunter Thomas · Arese, IT

Key dates

• Filing date: Nov 26, 1991
• Grant date: Jan 5, 1993
• Expiry date: Nov 26, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/56
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Substituted pyridyl-dihydroxy-heptenoic acid of the formula ##STR1## and its salts, if desired in an isomeric form, have a superior inhibitory action on HMG-CoA reductase and thus bring about a surprisingly good lowering of the cholesterol content in the blood.