Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides
US5177206A · kind A · utility
18Cited by
6References
9Claims
0Family size
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Key dates
| Filing date | Oct 8, 1991 |
| Grant date | Jan 5, 1993 |
| Priority date | — |
| Expiry date | Oct 8, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The preparation of N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides by the coupling of substituted 1,2,4-triazolopyrimidine-2-sulfonyl halides with aryl amines of substantially reduced nucleophilic reactivity is facilitated by conducting the reaction in the presence of a pyridine base and a catalytic amount of dimethyl sulfoxide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.