Lipoprotein removal by soluble enzymes
US5178864A · kind A · utility
7Cited by
6References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 14, 1990 |
| Grant date | Jan 12, 1993 |
| Priority date | — |
| Expiry date | Aug 14, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A therapeutically effective amount of soluble phospholipase A.sub.2 is administered into a subject for lowering the low density lipoproteins ("LDL") in the blood. Phospholipase A.sub.2 modifies the plasma LDL by hydrolyzing the phospholipids present in LDL. As a result, the modified LDL is rapidly removed from the bloodstream by the catabolic processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.