Patent · US Expired

Pilosinine derivatives

US5180837A · kind A · utility

1Cited by

1References

6Claims

0Family size

Assignee

MERCK PATENT GESELLSCHAFT MIT BESHRANK TER HAFTUNG · DE

Inventors

Ulrich Heywang · Darmstadt, DE
Michael Casutt · Pfungstadt, DE
Michael Schwarz · Pocking, DE

Key dates

Filing date	Oct 23, 1991
Grant date	Jan 19, 1993
Priority date	—
Expiry date	Oct 23, 2011

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P27/02
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to a process for the preparation of racemic pilosinine derivatives as precursor for the alkaloid pilocarpine of pharmacological importance from a 5-formyl-1-alkylimidazole of the formula I ##STR1## in which R.sup.1 is a straight-chain or branched alkyl chain with 1-6 C atoms which, via the stage of the thioacetal, is added onto .gamma.-crotonolactone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.