Certain oxazoloquinolinones; a new class of GABA brain receptor ligands
US5182290A · kind A · utility
27Cited by
1References
22Claims
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Assignee
Inventor
Key dates
| Filing date | Aug 27, 1991 |
| Grant date | Jan 26, 1993 |
| Priority date | — |
| Expiry date | Aug 27, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention encompasses compounds of the formula: ##STR1## and the pharmaceutically acceptable non-toxic salts thereof wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and W are variables These compounds are highly selective agonists, antagonists or inverse agonists for GABA.sub.a brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep and seizure disorders, overdose with benzodiazepine drugs, and enhancement of memory.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.