Apparatus for degassing a liquid
US5183486A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1990 |
| Grant date | Feb 2, 1993 |
| Priority date | — |
| Expiry date | Dec 4, 2010 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/30
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Methods and apparatus for effective vacuum degassing of a liquid are provided for liquid chromatography. The bottles with the liquid are mounted above the vacuum degassing unit to provide a head pressure to the LC pump and physical stability to the bottles. The liquid is heated in the vacuum chamber by a radiator of electromagnetic energy (in one embodiment, infra-red light). Alternatively the liquid is heated before it enters the vacuum chamber. The liquid is in an agitated state in the vacuum chamber. In one variation, the liquid is conducted through the vacuum chamber through tubes wound around bobbins so as to expose a greater portion of the surface area of the tubes to vacuum. Circuitry stops the vacuum pump for a duration of a chromatographic run. The circuitry controls the LC pump and the vacuum pump so as to optimize the chromatographic conditions in the liquid chromatography analytical system. The autosampler of the analytical system includes a vacuum degasser for degassing the resident solvents of the autosampler. Alternatively, the vacuum degassing unit for degassing the mobile phase is used to degas the resident solvents. The analytical system has its own vacuum chamber…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.