Process for the racemization of optically active 1-aryl-alkylamines
US5183939A · kind A · utility
8Cited by
7References
4Claims
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Key dates
| Filing date | Nov 21, 1991 |
| Grant date | Feb 2, 1993 |
| Priority date | — |
| Expiry date | Nov 21, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A new process for the racemization of optically active 1-aryl-alkylamines of the formula (I) ##STR1## in which Ar represents optionally substituted aryl and PA1 R represents alkyl, which is characterized in that compounds of the formula (I) which largely have the R- or S-configuration at the carbon atom marked by * are reacted with metal alkoxides in dimethyl sulphoxide, optionally in the presence of appropriate alcohols, at temperatures between 0.degree. C. and 200.degree. C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.