Method of packaging freeze dried vaccines in syringes and plug for implementing the method
US5184450A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 18, 1992 |
| Grant date | Feb 9, 1993 |
| Priority date | — |
| Expiry date | Feb 18, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2207/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
In a method of packaging freeze dried vaccine in a bypass syringe sterilized syringes are disposed in rows in an aseptic dispensing machine. Doses of a solution or suspension to be freeze dried are introduced into the syringes. A temporary plug is inserted in the same machine into the mouth of the syringe body in a position allowing communication between the interior of the syringe body and the exterior. The syringes are introduced into a freeze drying machine. The vaccine is freeze dried. At the end of the freeze drying cycle the temporary plug is depressed in a controlled atmosphere in the freeze drying machine into a hermetic sealing position. The syringes are transferred into an aseptic dispensing machine. The temporary plug is removed. An intermediate piston-plug is fitted. The dose of solvent is introduced and an end piston-plug is fitted.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.