Process for producing immunostimulants
US5185321A · kind A · utility
5Cited by
3References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 27, 1990 |
| Grant date | Feb 9, 1993 |
| Priority date | — |
| Expiry date | Nov 27, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Immunostimulant products are prepared by adding lysozyme to a culture of L.bulgaricus at a pH of from 4-8 and then incubating the culture to hydrolyze peptidoglycans of cell walls of the bacteria. A suspension containing the lysozyme-treated L.bulgaricus is collected, which is centrifuged to obtain an immunostimulant supernatant. The supernatant may be filtered to obtain an immunostimulant solution, which may be added to a fermented milk, or to a whey, to prepare an immunostimulant product. Alternatively, L.bulgaricus may be cultured and hydrolyzed by lysozyme in a milk product to provide an immunostimulant milk product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.