cDNA clone coding for Venezuelan equine encephalitis virus and attenuating mutations thereof
US5185440A · kind A · utility
75Cited by
0References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 20, 1989 |
| Grant date | Feb 9, 1993 |
| Priority date | — |
| Expiry date | Jun 20, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/36143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A DNA comprises a cDNA clone coding for an infectious Venezuelan Equine Encephalitis Virus RNA transcript and a heterologous promoter sequence positioned upstream from the cDNA clone and operatively associated therewith. A method of making a live attenuated Togavirus useful as a vaccine, and cDNA clones which code for attenuated Togaviruses, is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.