Process for the preparation of symmetrical diarylacetylenes

US5185454A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Axel Bader · Friedberg, DE
• Dieter Arlt · Cologne, DE

Key dates

• Filing date: Oct 2, 1990
• Grant date: Feb 9, 1993
• Expiry date: Oct 2, 2010

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C317/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Symmetrical diaryl-acetylenes can be prepared by reacting an aryl halide with acetylene in the presence of a palladium catalyst and a base. If the acetylene is introduced into the liquid reaction mixture using a high intensity gas dispersion means, the aryl halide used can be an aryl bromide.