Laminated composite for transdermal administration of fentanyl
US5186939A · kind A · utility
24Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1992 |
| Grant date | Feb 16, 1993 |
| Priority date | — |
| Expiry date | Jan 15, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A laminated composite for administering fentanyl transdermally that consists of a fentanyl-impermeable occlusive backing layer and an adhesive fentanyl reservoir layer comprising fentanyl dissolved in an amine-resistant polydimethylsiloxane that has a high diffusivity and poor solubility for fentanyl which enables the fentanyl to be released rapidly from the composite over a one day period with little residual fentanyl left in the reservoir thereafter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.