Method of hydroxylation with ATCC 55086
US5187074A · kind A · utility
22Cited by
4References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 20, 1992 |
| Grant date | Feb 16, 1993 |
| Priority date | — |
| Expiry date | Feb 20, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel dipeptide isostere is the biotransformed product after incubation with a culture of Streptomyces. It inhibits HIV protease, and is useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as a compound, pharmaceutically acceptable salt, pharmaceutical composition ingredient, whether or not as a prodrug or as a combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.