Leukaemia inhibitory factor

US5187077A · kind A · utility

Assignee

• AMRAD Corporation Limited · AU

Inventors

• David Gearing · Melbourne, AU
• Nicholas Martin Gough · Melbourne, AU
• Douglas Hilton · Melbourne, AU
• Julie Ann King · Melbourne, AU
• Donald Metcalf · Melbourne, AU
• Edouard Collins Nice · Melbourne, AU
• Nicos A. Nicola · Melbourne, AU
• Richard J. Simpson · Melbourne, AU
• Tracy Willson · Melbourne, AU

Key dates

• Filing date: Dec 9, 1988
• Grant date: Feb 16, 1993
• Expiry date: Dec 9, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/13043
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A leukaemia-inhibitory factor (LIF) is disclosed, together with a method of preparation of LIF in essentially pure form. Nucleotide and amino acid sequences are disclosed, together with recombinant DNA moleclues and host cells for production of polypeptides having LIF activity.