Patent · US Expired

S-nitroso-N-alkonoylpenicillamines

US5187305A · kind A · utility

14Cited by
7References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 26, 1990
Grant dateFeb 16, 1993
Priority date
Expiry dateNov 26, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F7/081
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to the compounds of formula (I), ##STR1## wherein R.sup.1 is C.sub.1-8 alkyl; C.sub.5-8 cycloalkyl;--(CH.sub.2).sub.n --Si(CH.sub.3).sub.3, wherein n is 1 to 5; C.sub.2-5 alkylenyl; arylmethylene; aryl; heteroaryl; or wherein such aryl or heteoaryl bears 1 to 3 substituents independently selected from halogen, amino, C.sub.1-8 alkyl mono- or disubstituted amino, C.sub.1-8 alkyl and C.sub.1-8 alkoxy and R.sup.2 is C.sub.1-8 alkoxy, pharmaceutical formulations containing these compounds and their use as vasodilators and in the treatment of cardiovascular disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.