Patent · US Expired

Encapsulated 2',5'-phosphorothioate oligoadenylates

US5188897A · kind A · utility

480Cited by

4References

27Claims

0Family size

Assignee

Temple University-Of The Commonwealth System of Higher Education · US

Inventors

Robert J. Suhadolnik · Roslyn, US
Wolfgang Pfleiderer · Konstanz, DE

Key dates

Filing date	Mar 26, 1990
Grant date	Feb 23, 1993
Priority date	—
Expiry date	Mar 26, 2010

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2984
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is PAC REFERENCE TO GOVERNMENT GRANT The invention described herein was made, in part, in the course of work supported by National Institutes of Health grant PO1 CA-29545 and National Science Foundation grant DMB84-15002.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.