Patent · US Expired

Method of determining the total fibrinolytic activity in the plasma

US5188940A · kind A · utility

6Cited by

1References

3Claims

0Family size

Assignee

Dr. Karl Thomae GmbH · DE

Inventors

Jurgen Krause · Biberach an der Riß, DE
Walter Haarmann

Key dates

Filing date	Jan 10, 1990
Grant date	Feb 23, 1993
Priority date	—
Expiry date	Jan 10, 2010

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/9726
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method of determining the total fibrinolytic activity in plasma, is characterized in that PA0 a) a quantity of fibrin sufficient to produce turbidity is added to a dilute platelet poor plasma sample or is produced in situ and the time dependent change in turbidity or the time-dependent formation of fibrin cleavage products is measured; or PA0 b) a chromogenic plasmin substrate and a quantity of fibrin, fibrinogen cleavage products or an enzyme which produces fibrin in situ, insufficient to produce turbidity, is added to a dilute platelet poor plasma sample and the time dependent color formation is measured.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.