Patent · US Expired

Heterocyclic substituted acylaminothiazoles, their preparation and pharmaceutical compositions containing them

US5189049A · kind A · utility

30Cited by
0References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1990
Grant dateFeb 23, 1993
Priority date
Expiry dateDec 5, 2010

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of formula ##STR1## in which R.sub.1 represents H, an alkyl or a substituted alkyl, R.sub.2 represents H or alkyl and R.sub.3 represents an optionally substituted cycloalkyl or an optionally substituted aromatic group, which can be a phenyl or a heterocyclic group comprising one or more hetero-atoms chosen from O, S and N, or R.sub.2 and R.sub.3 considered together represent the group ##STR2## which is optionally substituted on the phenyl ring, and Z represents a heterocycle comprising one or more heteroatoms chosen from O, S and N, fused with an aromatic ring which can comprise a hetero-atom and can be substituted, the said heterocycle being optionally substituted on N, when it comprises such an atom, by an alkyl or a substituted alkyl group, and the salts of these compounds with acids or bases. PA1 Use of these compounds as medicaments. PA1 No figure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.