Process for producing non-ionic radiographic contrast media utilizing N-allylation
US5191119A · kind A · utility
7Cited by
9References
7Claims
0Family size
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Key dates
| Filing date | Jul 5, 1990 |
| Grant date | Mar 2, 1993 |
| Priority date | — |
| Expiry date | Jul 5, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for substituting aromatic carboxylic acids and derivatives thereof and amino substituted aromatic carboxylic acids and derivatives thereof, by forming imides and imide-amides, respectively, by acylation with aliphatic carboxylic acids, substituting at least one nitrogen atom under mild basic conditions with an aliphatic compound having as alkylating agent a displaceable functionality and removing undesired acyl groups, as appropriate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.