Patent · US Expired

Method of inhibiting angiogenesis of tumors

US5192744A · kind A · utility

107Cited by
5References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 12, 1990
Grant dateMar 9, 1993
Priority date
Expiry dateJan 12, 2010

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method of inhibiting angiogenesis and preparations for use therein are disclosed. The preparations comprise human thrombospondin in trimer or monomer form or a fragment thereof capable of inhibiting vascularization. The method and preparations are especially applicable to the treatment of solid tumors including skin cancers for controlling tumor neovascularization and thereby arresting tumor enlargement.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.