Monoclonal antibodies reactive with a human atheroma associated antigen
US5196324A · kind A · utility
28Cited by
5References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 17, 1990 |
| Grant date | Mar 23, 1993 |
| Priority date | — |
| Expiry date | Oct 17, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/83
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a naturally occurring, minimally modified LDL antigen which is present in human atherosclerotic lesions as well as in the serum of a high percentage of patients with coronary artery disease. The invention also comprises antibodies reactive with the antigen, hybridoma cell lines that produce the antibodies of the inveniton, and methods for using the antibodies in the diagnosis and treatment of atherosclerotic disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.