Synthetic bioadhesive
US5197973A · kind A · utility
60Cited by
4References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 14, 1990 |
| Grant date | Mar 30, 1993 |
| Priority date | — |
| Expiry date | Dec 14, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
This invention pertains to a synthetic adhesive composition for use in aqueous environments. The composition comprises polypeptide chains having an .alpha.-helical structure in aqueous environments and capable of cohesive and adhesive interactions. The polypeptide chains comprise polar and apolar amino acids, the apolar and polar amino acids being arranged to define apolar and polar vertical spiraling stripes on the helix surface. The apolar stripes allow the polypeptide chains to aggregate into superhelical structures and the polar stripes allow interchain crosslinking within and between the superhelical structures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.