Patent · US Expired

Assay for gene deletion of GST-1 in human samples based on the polymerase chain reaction

US5198337A · kind A · utility

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Assignee

Inventors

Key dates

Filing dateApr 13, 1990
Grant dateMar 30, 1993
Priority date
Expiry dateApr 13, 2010

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/811
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Methods for the detection of GST-1 gene deletion in human blood or tissue samples. The polymerase chain reaction is used to identify the presence or absence of the GST-1 gene in human clinical samples as a means of assessing susceptibility to neoplasia or toxicity upon chemical exposure. The method may also be used on human tumor samples to assess the possibility of resistance to certain chemotherapeutic agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.