Derivatives of 1,2-dihydro 2-oxo quinoxalines, their preparation and their use in therapy
US5198441A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1991 |
| Grant date | Mar 30, 1993 |
| Priority date | — |
| Expiry date | Jun 17, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New derivatives of 1,2-dihydro 2-oxo quinoxalines corresponding to the general formula I: ##STR1## in which: R is a hydrogen or halogen atom PA1 R.sub.1 is a hydrogen atom or a straight or branched C.sub.1 -C.sub.4 alkyl radical PA1 R.sub.2 is: PA2 a hydrogen atom PA2 a C(O)R.sub.4 radical in which R.sub.4 is a straight or branched C.sub.1 -C.sub.4 alkyl group PA2 a C(O)NHR.sub.5 radical in which R.sub.5 is a straight or branched C.sub.1 -C.sub.4 alkyl radical or a phenyl group PA1 A is a C.sub.1 -C.sub.4 alkaline chain PA1 R.sub.3 represents: PA2 a hydrogen atom, a C.sub.1 -C.sub.4 alkyl radical, a C.sub.3 -C.sub.6 cycloalkyl radical, an alcynyl, nitrile, hydroxyl, carboxamido, pyridyl, phenyl group, or a phenyl group substituted by a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group or a nitro group PA2 an alkenyl radical of the formula: ##STR2## in which R.sub.6, R.sub.7 may, independently of each other, be a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group, a phenyl group or an alkoxycarbonyl group PA2 a radical of the formula: EQU --OC(O)R.sub.8 PA2 in which R.sub.8 represents a C.sub.1 -C.sub.4 alkyl radical PA2 a radical of the formula: EQU --OC(O)NH…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.