Process for the production of gramine derivatives

US5198553A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Wolfgang Kubler · Berlin, DE
• Gregor Haffer · Berlin, DE
• Reiner Wierzchowski · Berlin, DE
• Klaus Nickisch · Berlin, DE

Key dates

• Filing date: Dec 26, 1991
• Grant date: Mar 30, 1993
• Expiry date: Dec 26, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the production of gramine derivatives is described, which is characterized in that an indole is reacted with an imine under acid catalysis in the presence of primary amines.