Process for improving mass transfer in a membrane bioreactor and providing a more homogeneous culture environment
US5202254A · kind A · utility
68Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 11, 1990 |
| Grant date | Apr 13, 1993 |
| Priority date | — |
| Expiry date | Oct 11, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M41/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for improving mass transfer in a bioreactor having at least one semi-permeable membrane defining first and second chambers on opposite sides of the membrane provides for circulating a first media including nutrients and the like through the first chamber and for circulating a second media for cell culture through the second chamber of the bioreactor. The first and second media may be circulated through a plurality of bioreactors connected in parallel while balancing the flow in each reactor. The flow in the second circuit can be periodically reversed to provide increased cell culture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.