Resolution of .alpha.-tertiary carboxylic acid esters using lipase from Candida lipolytica
US5202260A · kind A · utility
7Cited by
4References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 8, 1991 |
| Grant date | Apr 13, 1993 |
| Priority date | — |
| Expiry date | May 8, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P41/005
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for the resolution of .alpha.-tertiary carboxylic acid esters by partial hydrolysis is disclosed. The partial hydrolysis is carried out by contacting the esters with an aqueous solution in the presence of a lipase derived from Candida lipolytica, and the hydrolysis product is separated from unreacted starting material to obtain the hydrolysis product or the unreacted starting material in enantiomerically enriched form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.