Cocaine and cocaine metabolites assay tracers, immunogens and antibodies
US5202270A · kind A · utility
12Cited by
15References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 1990 |
| Grant date | Apr 13, 1993 |
| Priority date | — |
| Expiry date | Aug 30, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/825
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed to a fluorescence polarization assay for benzoyl ecgonine and substituted benzoyl ecgonine compounds in biological fluids, and to a method of making reagents therefor. Specifically, tracers, immunogens and antibodies are disclosed. The tracers and the immunogens are made from substituted benzoyl ecgonine compounds. A fluorescein moiety is included in the tracer, while a poly(amino acid) forms a part of the immunogen. The assay is conducted by measuring the degree of polarization retention of plane polarized light that has been passed through a sample containing antiserum and tracer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.