2-thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters
US5202330A · kind A · utility
27Cited by
9References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1987 |
| Grant date | Apr 13, 1993 |
| Priority date | — |
| Expiry date | Jan 5, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pyrimidine compounds of the formula ##STR1## wherein X is sulfur or oxygen, Y is R.sub.11 or --O--R.sub.1, and R.sub.4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents, particularly anti-hypertensive agents, due to their calcium entry blocking vasodilator activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.