Patent · US Expired

Process for purifying 7-dimethylamino-6-demethyl-6-deoxytetracycline

US5202449A · kind A · utility

9Cited by
2References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 27, 1991
Grant dateApr 13, 1993
Priority date
Expiry dateAug 27, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C231/24
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A process for purifying 7-dimenthylamino-6-demethyl-6-deoxytetracycline represented by the following formula, ##STR1## which comprises dissolving 7-dimethylamino-6-demethyl-6-deoxytetracycline or its hydrochloride having a lower purity in a mixed solvent of an alcohol and water by using hydrochloric acid and then adjusting the pH of the solution to 3.5 to 4.5 to recrystallize the hydrochloride having a higher purity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.