.alpha.-trifluoromethyl-substituted, saturated bicyclic amines

US5204471A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Michael Negele · Cologne, DE
• Dieter Habich · Wuppertal, DE
• Christian Laue · Monheim, DE
• Heinz Ziemann · Leichlingen, DE

Key dates

• Filing date: Jul 24, 1992
• Grant date: Apr 20, 1993
• Expiry date: Jul 24, 2012

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D215/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New .alpha.-trifluoromethyl-substituted, saturated bicyclic amines of the formula ##STR1## in which R.sup.1 represents hydrogen, C.sub.1 - to C.sub.8 -alkyl or C.sub.1 - to C.sub.8 -alkoxy, PA0 R.sup.2 represents hydrogen or C.sub.1 - to C.sub.4 -alkyl, PA0 n represents zero or 1, PA0 A represents ##STR2## B represents NH or ##STR3## and C represents ##STR4## in which A, B and C are either each different from one another or C represents ##STR5## and one of A and B represents NH and the other represents ##STR6## and R.sup.3 denotes hydrogen or C.sub.1 - to C.sub.4 -alkyl and the ring D is saturated.