Amphipathic compound and liposome comprising the same
US5206027A · kind A · utility
13Cited by
1References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 11, 1992 |
| Grant date | Apr 27, 1993 |
| Priority date | — |
| Expiry date | Aug 11, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06078
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An amphipathic compound, which includes a succinic acid moiety and an amino acid moiety and is designed so as to form a stable unilayer liposome, and a negatively charged liposome comprising said amphipathic compound as a membrane-component are disclosed. The amphipathic compound of the present invention gives liposomes which minimize the leakage of a drug encapsulated therein and scarcely undergo association, aggregation or precipitation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.