Process for the preparation of a particulate antimicrobial product, antimicrobial product obtained and applications thereof
US5206156A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 1990 |
| Grant date | Apr 27, 1993 |
| Priority date | — |
| Expiry date | May 11, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N11/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of a particulate antimicrobial product from the LP system of the lactoperoxidase enzyme/oxygen donor/oxidizable substrate (if needed). The process comprises bonding the lactoperoxidase enzyme to a particulate carrier comprising a polysaccharide nucleus, a first lipidic layer and a second phospholipidic layer in such a manner that the enzyme molecules are inserted into this second layer and/or into the first layer. The product according to the invention is obtained by then conditioning in a non-aqueous medium the aforesaid particulate vector and the molecules of the LP system not integrated into said vector. The process of the invention permits adjusting the diffusability of the product and its mobility as a function of the intended applications, without destruction of the LP system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.