Patent · US Expired

Spiro(4.5.)decane compounds

US5206247A · kind A · utility

17Cited by
2References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 5, 1991
Grant dateApr 27, 1993
Priority date
Expiry dateSep 5, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The compounds are 8-substituted 1-oxa-2-oxo-3,8-diazaspiro [4.5]decanes useful for the treatment of dyslipidaemiae, atherosclerosis and pathologies in which membrane lipid peroxidation plays an initiating and/or aggravating role. A compound disclosed is (R,S)-8-[3(3,5-di-tert.-butyl-4-hydroxyphenylthio)-2-hydroxypropyl]-1-oxa- 2oxo-3,8-diazaspiro [4.5]decane.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.