Facile synthesis of arylmaleic acids and anhydrides
US5206392A · kind A · utility
2Cited by
1References
13Claims
0Family size
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Key dates
| Filing date | Apr 27, 1992 |
| Grant date | Apr 27, 1993 |
| Priority date | — |
| Expiry date | Apr 27, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for making acrylmaleic acid and arylmaleic anhydride derivative useful as intermediates for the preparation of arylmaleimides in the synthesis of compounds having activity in the central nervous system. The process involves reacting arylacetonitriles with glyoxylic acid to provide novel intermediate 3-aryl-3-cyanopropeneoates which may be converted to the arylmaleic acid and arylmaleic anhydride derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.