Paramagnetic compounds

US5208324A · kind A · utility

Assignee

• NYCOMED IMAGING AS · NO

Inventors

• Jo Klaveness · Oslo, NO
• Pal Rongved · Oslo, NO
• Per Strande · Oslo, NO

Key dates

• Filing date: Jul 26, 1990
• Grant date: May 4, 1993
• Expiry date: Jul 26, 2010

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/24
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There are provided paramagnetic compounds comprising a paramagnetic metal species chelated by a chelating moiety bound by an amide group to a linker group itself bound by an ester group to a macromolecule, wherein said linker group provides a carbon chain of at least 2 atoms between said amide group and said ester group. The novel compounds are particularly suitable as contrast agents, e.g. in magnetic resonance imaging.