Immunization against Babesiosis using purified merozoite surface antigens of Basesia bigemina
US5209929A · kind A · utility
2Cited by
1References
11Claims
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Key dates
| Filing date | Mar 1, 1991 |
| Grant date | May 11, 1993 |
| Priority date | — |
| Expiry date | Mar 1, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/82
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antigenic surface proteins from the intraerythrocytic merozoite stage of Babesia bigemina have been isolated using cell fusions and monoclonal antibodies produced thereby. Immunization of mammals, such as bovines, with purified isolates induces an immunological response that is effective to reduce pathological effects of babesiosis induced by Babesia bigemina. Diagnostic kits using monoclonal antibodies and antigenic surface proteins of Babesia bigemina are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.