Patent · US Expired

Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists

US5210079A · kind A · utility

33Cited by

15References

31Claims

0Family size

Assignee

E.I. DU PONT DE NEMOURS AND COMPANY · US

Inventors

David J. Carini · Wilmington, US
John J. V. Duncia · Newark, US
Pancras C. Wong · Wilmington, US

Key dates

Filing date	Feb 7, 1992
Grant date	May 11, 1993
Priority date	—
Expiry date	Feb 7, 2012

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/6558
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Substituted imidazoles such as 2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-5-(hydroxy methyl)imidazole and 2-butyl-4-chloro-1-[(2'-carboxybiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imi dazole and pharmaceutically acceptable salts thereof are useful for treating chronic renal failure, mediated by angiotensin-II.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.