Compositions and methods for introducing effectors to pathogens and cells
US5212075A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1991 |
| Grant date | May 18, 1993 |
| Priority date | — |
| Expiry date | Apr 15, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/61
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods for the inhibition and prevention of pathogenic infection and neoplastic disease are provided. The compositions include hybrid molecules having a binding moiety and an effector moiety joined by a linker region. When administered to a host, the binding moiety, such as a carbohydrate, attaches to a receptor, such as a conserved lectin receptor on the pathogen or neoplastic cell, and the effector moiety provides an invariant antigenic determinant for eliciting or modulating an immune response. The effector moiety may also be a drug or other compound which inhibits growth of a bound pathogen or cell. Compositions comprising the hybrid molecule in a suitable pharmaceutical carrier are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.