Method for analysis of catecholamine
US5212097A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 20, 1990 |
| Grant date | May 18, 1993 |
| Priority date | — |
| Expiry date | Nov 20, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/203332
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Catecholamines in a living body fluid are analyzed by a process which involves reacting a living body fluid sample with a boron compound of the formula: ##STR1## wherein R is hydroxyl, aryl or alkyl, to form a complex of the boron compound with a catecholamine; deproteinizing the reaction solution containing the complex; decomposing the complex to release the catecholamine; labeling the released catecholamine to form a labeled catecholamine; eluting the labeled catecholamine adsorbed on a separation column; and detecting the eluted, labeled catecholamine. Advantageously, this process enables catecholamines to be measured with a high recovery ratio and high accuracy by forming the catecholamines into a complex with a boron compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.