Alkylaminoalkylamine and ether compounds, processes and intermediates for their preparation, and medicaments containing them

US5212173A · kind A · utility

Assignee

• Kali-Chemie Pharma GmbH · DE

Inventors

• Herman Kraehling · Sehnde, DE
• Samuel David · Dorval, CA
• Insa Hell · Hannover, DE
• Ulf Preuschoff · Laatzen, DE
• Ivan Ban · Hannover, DE
• Marie-Odile Christen · Paris, FR

Key dates

• Filing date: Dec 19, 1991
• Grant date: May 18, 1993
• Expiry date: Dec 19, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/42
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Pharmacologically active compounds corresponding to the formula I ##STR1## in which n represents 2-5, PA0 m represents 2-6, PA0 R.sup.1 denotes hydrogen or lower alkyl, PA0 R.sup.2 represents an OR.sup.4 group in which R.sup.4 denotes lower alkyl or a phenyl or phenyl-lower alkyl group which is optionally substituted in the phenyl ring, or PA0 R.sup.2 represents a ##STR2## group in which R.sup.5 and R.sup.6 independently of one another each denote hydrogen, lower alkyl or a phenyl or phenyl-lower alkyl group which is optionally substituted in the phenyl ring, or PA1 R.sup.5 and R.sup.6, together with the nitrogen atom to which they are bonded, represent a saturated 5- or 6-membered heterocycle, PA0 R.sup.3 represents a saturated monocyclic or bicyclic hydrocarbon group which is derived from terpenes and has 10 or 11 carbon atoms, and PA0 Z represents oxygen or, if R.sup.3 is a dihydronopyl group, Z may also represent sulfur, and salts thereof.