Method and apparatus for two-dimensional measurement of concentration of biological macromolecule solution
US5214288A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 18, 1991 |
| Grant date | May 25, 1993 |
| Priority date | — |
| Expiry date | Dec 18, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/33
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of making a two-dimensional measurement of the concentration of a biological macromolecule aqueous solution and an apparatus for carrying out this method are disclosed. By charging the biological macromolecule aqueous solution and an aqueous crystallizing agent solution into a crystallizing cell, irradiating the crystallizing cell with an ultraviolet light from an ultraviolet light source, two-dimensionally scanning the ultraviolet light transmitted through the crystallizing cell by a linear image sensor to detect the quantity of the transmitted light, and carrying out a conversion of the detected quantity of the transmitted light to the protein concentration, the process of a crystallization of the biological macromolecule from biological macromolecule aqueous solution can be easily and accurately twodimensionally measured.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.