Patent · US Expired

Preparation of pharmaceutical and other matrix systems by solid-state dissolution

US5215756A · kind A · utility

31Cited by

6References

13Claims

0Family size

Inventors

Dilip J. Gole · Ann Arbor, US
R. Saul Levinson · Harrisburg, US
James Carbone · Grafton, US
J. Desmond Davies · Grosse Pointe Farms, US

Key dates

Filing date	Nov 6, 1990
Grant date	Jun 1, 1993
Priority date	—
Expiry date	Nov 6, 2010

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2800/56
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method is disclosed for preparing pharmaceutical and other matrix systems that comprises solidifying a matrix composition dissolved or dispersed in a first solvent and subsequently contacting the solidified matrix with a second solvent that is substantially miscible with the first solvent at a temperature lower than the solidification point of the first solvent, the matrix components being substantially insoluble in the second solvent, whereby the first solvent is substantially removed resulting in a usable matrix.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.