Patent · US Expired

Method for the determination of an ion with increased sensitivity, use of substances which are suitable for this and a corresponding agent

US5215924A · kind A · utility

3Cited by

2References

7Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Walter Rittersdorf · Mannheim, DE
Werner Guethlein · Mannheim, DE
Detlef Thym · Mannheim, DE
Peter Vogel · Diepersdorf, DE

Key dates

Filing date	May 10, 1991
Grant date	Jun 1, 1993
Priority date	—
Expiry date	May 10, 2011

Classification

Technology area (CPC G)Physics
CPC primaryG01N31/22
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to a method for determining an ion in an aqueous sample. The method involves contacting the sample with a water immiscible material including an ionophore, a pH indicator and a compound which stabilizes sensitivity of the assay. The ion reacts with the ionophore in the water immiscible material, releasing a proton which reacts with the pH indicator generating a color change which is representative of the ion to be measured. The stabilizing compound stabilizes this change. Also described are compositions including the three recited elements, and various new compounds useful as the stabilizer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.